The Incidence and Prevalence of Epilepsy in the United Kingdom 2013-2018: a retrospective cohort study of UK primary care data.

The estimated incidence (50-80 per 100,000 person-years) and prevalence rates (5-10 per 1000 person / year) for epilepsy have been found to be relatively consistent across high income countries [1–3]. Nevertheless, changes in demographics and risk factors mean that the epidemiology of epilepsy may change over time. For instance, in countries with an aging population, the increasing prevalence of diseases of old age such as stroke or dementia could increase the prevalence of epilepsy. Conversely, improved General Practitioner (GP) and ...

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EFFECTS OF PROGRESSIVE MUSCLE RELAXATION EXERCISES ON PATIENTS WITH EPILEPSY ON LEVEL OF DEPRESSION, QUALITY OF SLEEP, AND QUALITY OF LIFE: A RANDOMIZED CONTROLLED TRIAL

For many epilepsy patients, the problems accompanying epilepsy are more severe than seizures [1]. Studies show that depression is more common in epilepsy patients than in the general population [2–4]. Elger and Hoppe (2011) considered depression in epilepsy patients as learned helplessness against exposure to chronic stress due to life difficulties caused by epilepsy and against the threat of seizure [5]. Sleep problems are also quite common in epilepsy patients due to the drugs used and disease-related psychosocial causes.

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The net impact of clinical seizures on outcome characteristics in infants with neonatal encephalopathies at 12 months of age

Neonatal encephalopathy (NE) is one of the most common neurological disorders in the neonatal intensive care unit (NICU). Recent diagnostic advances have changed the etiologic distribution of NE in preterm and term newborns in the last decade [1–6]. Neuroimaging studies using magnetic resonance imaging modalities, such as conventional, diffusion, and spectroscopy, provide a helpful guide regarding the etiologic definition and the pattern of brain injury [7]. Detecting the exact etiology of NE in each newborn has implications for optimal treatment, ...

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Variation in access to specialist services for neurosurgical procedures in patients with epilepsy in England, a cohort study

Despite numerous pharmacological options for people with epilepsy, the goal of seizure freedom without side-effect burden remains elusive for a large proportion of individuals. Treatment with anti-seizure medications (ASMs) typically starts with one ASM, whereafter the individual’s regimen is adapted with changes to drug and dose until seizures are controlled and the treatment is tolerated [1].

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Vague retellings of personal narratives in temporal lobe epilepsy

Circumstantial language in individuals with temporal lobe epilepsy (TLE) is clinically identifiable and describes a pedantic, repetitive, and overly detailed output style [1–3]. This can be distinguished from tangentiality which is characterised by meandering and often irrelevant content. TLE is frequently associated with cognitive-linguistic impairments [4] which, in current practice, are most commonly demonstrated on neuropsychological examination at a single-word level, such as on tasks of confrontation naming [5,6].

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Dysautonomia in people with epilepsy: A scoping review

Epilepsy is one of the most common neurologic diseases and affects over 70 million people worldwide [1]. The estimated global burden of epilepsy accounts for 5% of the total neurological disability-adjusted life years (DALYs) [2]. Not only is the quality of life lessened in patients with epilepsy, but they also have a higher risk (three times or greater) of dying from sudden cardiac death compared to the general population [3]. The standardized mortality rate in epilepsy patients in high-income countries ...

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