Unraveling complex relationships among dysphoric disorder, localization-related epilepsy, and mood disorders

Publication date: October 2017Source:Epilepsy & Behavior, Volume 75
Author(s): Tetsufumi Suda, Yasutaka Tatsuzawa, Taichi Mogi, Aihide Yoshino

Background
Dysphoric disorder (DD), characterized by intermittent pleomorphic symptoms, has been believed to be specific to epilepsy. However, our previous study revealed that DD in patients with localization-related epilepsy was associated with a lifetime diagnosis of mood disorders. The present study was conducted to estimate the prevalence ...

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Provision of sudden unexpected death in epilepsy (SUDEP) information among Malaysian parents of children with epilepsy

Publication date: October 2017Source:Epilepsy & Behavior, Volume 75
Author(s): Choong Yi Fong, Wei Kang Lim, Ann Nie Kong, Pei Lin Lua, Lai Choo Ong
Sudden unexpected death in epilepsy (SUDEP) is an important cause of mortality in epilepsy. To date, there is only one published UK study evaluating information provision of SUDEP among parents of children with epilepsy (CWE), and there ...

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Clinical utility of serum lactate levels for differential diagnosis of generalized tonic–clonic seizures from psychogenic nonepileptic seizures and syncope

Publication date: October 2017Source:Epilepsy & Behavior, Volume 75
Author(s): Ebru Apaydın Doğan, Ali Ünal, Aslıhan Ünal, Çağla Erdoğan

Background
The differential diagnosis of generalized tonic–clonic seizures (GTCS), psychogenic nonepileptic seizures (PNES), and syncope constitutes a major challenge. Misdiagnosis rates up to 20 to 30% are reported in the literature.
Purpose
To assess the clinical utility of serum lactate levels for differentiation of ...

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An acidosis-sparing ketogenic (ASK) diet to improve efficacy and reduce adverse effects in the treatment of refractory epilepsy

Publication date: September 2017Source:Epilepsy & Behavior, Volume 74
Author(s): Alan W.C. Yuen, Isabel A. Walcutt, Josemir W. Sander
Diets that increase production of ketone bodies to provide alternative fuel for the brain are evolving from the classic ketogenic diet for epilepsy devised nearly a century ago. The classic ketogenic diet and its more recent variants all appear to have similar efficacy with approximately 50% of ...

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Neurobehavioral consequences of continuous spike and waves during slow sleep (CSWS) in a pediatric population: A pattern of developmental hindrance

Publication date: September 2017Source:Epilepsy & Behavior, Volume 74
Author(s): Valentina De Giorgis, Melissa Filippini, Joyce Ann Macasaet, Silvia Masnada, Pierangelo Veggiotti

Introduction
Continuous spike and waves during slow sleep (CSWS) is a typical EEG pattern defined as diffuse, bilateral and recently also unilateral or focal localization spike–wave occurring in slow sleep or non-rapid eye movement sleep. Literature results so far point out ...

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Topiramate-associated sexual dysfunction: A systematic review

Publication date: August 2017Source:Epilepsy & Behavior, Volume 73
Author(s): Louis Wei-Hsi Chen, Melody Yun-Si Chen, Kuo-Yen Chen, Hung-Sheng Lin, Chia-Chang Chien, Hsin-Ling Yin

Introduction
Sexual pharmacotoxicity renders patients with epilepsy at a risk for sexual dysfunction (SD). This study is aimed to analyze the relationship between sexual function and topiramate to avoid topiramate-associated SD.
Methods
A systematic review ...

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Impaired responsibility dimension of self-esteem of Brazilian adolescents with epilepsy

Publication date: August 2017Source:Epilepsy & Behavior, Volume 73
Author(s): Nathália F. Siqueira, Fernando L.B.B. Oliveira, Elisabete Abib Pedroso de Souza
This study aimed to compare the self-esteem of Brazilian adolescents with epilepsy and Brazilian adolescents without this condition and the correlations between self-esteem of these adolescents with depression and anxiety symptoms. Study participants were 101 adolescents of both sexes, aged 10–19years old, from elementary ...

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Analytic information processing style in epilepsy patients

Publication date: August 2017Source:Epilepsy & Behavior, Volume 73
Author(s): Marzia Buonfiglio, Francesco Di Sabato, Silvia Mandillo, Mariarita Albini, Carlo Di Bonaventura, Annateresa Giallonardo, Giuliano Avanzini
Relevant to the study of epileptogenesis is learning processing, given the pivotal role that neuroplasticity assumes in both mechanisms.Recently, evoked potential analyses showed a link between analytic cognitive style and altered ...

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Cognitive outcome after epilepsy surgery in children: A controlled longitudinal study

Publication date: August 2017Source:Epilepsy & Behavior, Volume 73
Author(s): Valentina Sibilia, Carmen Barba, Tiziana Metitieri, Giovanni Michelini, Flavio Giordano, Lorenzo Genitori, Renzo Guerrini

Objective
To analyze the determinants of cognitive outcome two years after surgery for drug-resistant epilepsy in a cohort of 31 children when compared to a control group of 14 surgical candidates who had yet to ...

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Atomoxetine, a norepinephrine reuptake inhibitor, reduces seizure-induced respiratory arrest

Publication date: August 2017Source:Epilepsy & Behavior, Volume 73
Author(s): Honghai Zhang, Haiting Zhao, Hua-Jun Feng
Sudden unexpected death in epilepsy (SUDEP) is a devastating epilepsy complication, and no effective preventive strategies are currently available for this fatal disorder. Clinical and animal studies of SUDEP demonstrate that seizure-induced respiratory arrest (S-IRA) is the primary event leading to death after generalized seizures in many cases. Enhancing brain ...

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