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Epilepsy affects approximately 70 million individuals worldwide [1]. In general, antiseizure medications (ASMs) are the mainstay of epilepsy treatment. Although there have been several newly-developed ASMs launched i.e., more than 25 ASMs to be prescribed for patients over past decades, some patients still suffer from ongoing seizures without attaining seizure freedom [2]. The next options for these patients include consideration for other treatment approaches including epilepsy surgery, diet therapy or neuromodulations.