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Status epilepticus (SE) is one of the most common neurologic emergencies in children.[1] Refractory SE (RSE) is defined as the failure of initial treatment with a benzodiazepine and a sequential antiseizure medication (ASM) with a different mechanism of action.[2] Although the incidence of RSE is difficult to estimate due to variability of definitions across studies, it is reported in approximately one-third of adults,[3,4] and 26-59% of children who presented with SE.[5-7] Prolonged SE is associated with worse neurological outcomes – i.e.