Anabolic-androgenic steroids abuse-induced seizures: a case report in a young male bodybuilder

Anabolic-androgenic steroids (AAS) are synthetic variations of Testosterone with anabolic effects. The prevalence rate of AAS use among gym attendees has been shown up to 70%. (1) Side effects of AAS are diverse, from subtle mood disturbances to multiple organ failure. In addition, AAS are often used in conjunction with other drugs to enhance performance or physique. “Steroid-accessory” drugs used by bodybuilders such as insulin, diuretics and thyroxine, can also precipitate medical emergencies including seizures (see supplementary section).

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Complete callosotomy in children with drop attacks; A retrospective monocentric study of 50 patients

Drop attacks occurring during drug-resistant epilepsy are a source of major deterioration in the quality of life of patients and may be responsible for severe traumatic injury [1]. Epileptic drop attacks are sudden falls due to atonic, tonic, myoclonic seizures or infantile spasms. Therapeutic options are limited and patients are often forced to wear a helmet at all times or even to remain seated and strapped to a seat. The fall is most often due either to a loss of ...

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Predictors of seizures in patients with cerebral venous thrombosis in the Thai population: A retrospective study

Cerebral venous thrombosis (CVT) is a potentially fatal venous occlusive condition that presents in the brain. Although headache is a common presentation in CVT [1], it shows insufficient specificity to trigger CVT diagnostics, which may cause delays in treatment. Moreover, clinical presentation that includes focal weakness, cranial neuropathy, or seizure tends to warrant neuroimaging examinations, improving the timing of CVT diagnosis [1,2].

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Analysis of Power Spectrum and Phase Lag Index Changes following Deep Brain Stimulation of the Anterior Nucleus of the Thalamus in Patients with Drug-Resistant Epilepsy: A Retrospective Study

Objectives: The mechanisms underlying the anterior nucleus of the thalamus (ANT) deep brain stimulation (DBS) for the treatment of drug-resistant epilepsy (DRE) have not been fully explored. The present study aimed to measure the changes in whole-brain activity generated by ANT DBS using interictal electroencephalography (EEG).Materials and Methods: Interictal EEG signals were retrospectively collected in 20 DRE patients who underwent ANT DBS surgery. Patients were classified as responders or non-responders depending on their response to ANT DBS treatment.

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Cortical myoclonus associated with coeliac disease showing a characteristic EEG pattern: A case report.

Coeliac disease (CD) is an immune-mediated enteropathy that may cause a broad spectrum of intestinal and extra-intestinal manifestations. Among them, neurological symptoms are present in up to one-third of the CD cases, including ataxia, epilepsy and myoclonus. The presence of any neurological symptom in a patient with CD must warn us of a possible complication of this immune-mediated disorder. However, neurological complications may precede the diagnosis of CD, and other possible causes need to be ruled out before attributing the ...

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Hippocampal injury in patients with status epilepticus: quantitative analysis of hippocampal volume and structural co-variance network

Status epilepticus (SE) is defined as a condition resulting either from the failure of the mechanisms responsible for seizure termination or the initiation of mechanisms that lead to abnormally prolonged seizures (after time point t1). SE can have long-term consequences (after time point t2), including neuronal death, neuronal injury, and alteration of neuronal networks, depending on the type and duration of seizures [1]. This brain damage can be identified by MRI, mainly through signal changes in diffusion restriction imaging or ...

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Neuropsychological Features of Mind wandering in Left-, Right- and Extra Temporal Lobe Epilepsy

The human mind can have thoughts that are unrelated to the current surrounding, frequently called “task-unrelated thoughts” or “mind wandering” (MW). Studies demonstrated that MW occupies 25 – 50 % of our waking life and occurs during almost every daily activity [1]. MW was shown to be a complex and multidimensional process (for an overview, see [2]). Here, we focus on the propensity and meta-awareness of MW.

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Automated spike detection: which software package?

Detecting interictal epileptiform discharges (IEDs) is helpful in epilepsy diagnosis [1,2]. Prolonged EEG recordings improve the chances of finding interictal activity, yielding higher diagnostic efficiency, but also needing more review time [3,4]. The typical procedure for reviewing a prolonged EEG record involves human scrutiny of the complete record, which is time-consuming.

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Phenotypic and genetic spectrum in Chinese children with SCN8A-related disorders

Epilepsy, known as seizure disorder, is one of the most common neurological condition with a prevalence of 12/1000 per year. It is diagnosed after a person has had at least two unprovoked or reflex seizures (or after one seizure with a high risk for more) [1]. The epileptic encephalopathy in children was re-defined as a condition where the epileptic activity itself contributes to severe cognitive and behavioral impairments above and beyond what might be expected from the underlying pathology alone.

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