Seizure

Narrative Medicine (NM) is a communication therapy that engages the patient’s story of illness or injury and treatment in the context of their identity, values, fears, and hopes. The NM practitioner invites the patient to put significant experiences into words and share in a dialogue where unstated concerns can be given voice and new insights can be discovered. Patients may also respond to prompts for journal writing that may be discussed with the NM provider and in workshop groups. NM ...

We describe a case of intracranial dural arteriovenous fistula (dAVFs) in left parieto-insulo-occipital regions and left cerebellum presenting with acute myelopathy followed by focal status epilepticus in a two-step clinical course.

Fırat et al. [1] discussed the potential drug-drug interactions between antiepileptic drugs and therapeutic drugs currently used in the management of coronavirus disease 2019 (COVID-19). This piece of discussion is relevant and indeed is of utmost importance given that clinicians specialized in the management of COVID-19 may not be familiar with the use of antiepileptic drugs and thus they may be of little knowledge how best to manage the potential drug-drug interactions involving antiepileptic drugs and the therapeutic drugs for ...

Tuberous sclerosis complex (TSC) is a well-known autosomal dominant multisystem disorder characterized by hamartomas in different organs.1 Mutations in TSC1 and TSC2 genes encoding hamartin and tuberin, respectively, suppress the mammalian target of rapamycin (mTOR) inhibition leading to the disruption of the regulation of cell proliferation and differentiation.1 The neurological complications of TSC, includes epilepsy, cognitive impairment, and autism, and about 75% of patients had pharmacoresistant epilepsy.

Brivaracetam (BRV) is a high-affinity synaptic vesicle glycoprotein 2A ligand (SV2A) that is currently licensed as monotherapy or adjunctive therapy for the treatment of focal-onset seizures in people with epilepsy aged ≥ 4 years [1]. After oral administration, BRV is rapidly and completely absorbed; it has low (< 20%) plasma protein binding and a linear and predictable pharmacokinetic profile [2]; furthermore, it carries low risks of drug–drug interactions [3]. Recently, BRV has gained interest for its use in emergency situation ...

The results of a brief literature search using PubMed including the years 1990–2018, and using the search terms next generation, training, and healthcare professionals or scientists, exemplify the importance of youth engagement. Every health-related area from human to veterinary medicine is devoting substantial attention to this topic. Almost 2000 articles are published in the last 30 years, with a marked increase in the last 2 decades. Science and healthcare occupy about a third of these publications [Fig.

Quality of life (QOF) is a health aspect that has become more and more relevant in the world as people with chronic conditions present a higher survival rate [1]. Questionnaires and other useful tools have been designed for the assessment of quality of life in various pathologies worldwide, from which some of them are validated in Spanish [2–5]. For children and adolescents with epilepsy, there are two scales in Spanish, one from Spain and one from Mexico, which are applied ...

Anti–leucine-rich glioma-inactivated 1 (anti-LGI1) encephalitis is a rare autoimmune disorder that presents with a triad of cognitive and psychiatric disturbances, hyponatremia, and autoimmune epilepsy. Facial-brachial dystonic (FBD) seizures are considered a pathognomonic sign of this condition. However, more subtle seizure types can occur and should be recognized, allowing for timely diagnosis and treatment. We report a case of anti-LGI1 autoimmune encephalitis presenting as orbitofrontal syndrome with focal “goosebump” seizures.

“The patient’s half, that he can contribute to knowledge, is ignored” (Evans, The Nightingale Silenced).

Osteoporosis is the most common bone disorder and is estimated to affect more than 200 million people worldwide (1). Osteoporosis is a chronic multifactorial disease characterized by decreased bone mineral density (BMD) due to an imbalance in the bone remodeling process which leads to porous bones, impaired structural integrity, decreased strength, and an increased risk of fractures (2). According to WHO, the definition of osteoporosis is a BMD ≤ -2.5 standard deviations (SD) below the average for a young healthy ...