Seizure

Epilepsy is an extremely widespread and serious neurological disease [1]. Psychiatric disorders have been observed in epilepsy patients, decreasing their quality of life and negatively affecting the course of illness [2]. Although comorbidities of psychiatric disorders are prevalent in epilepsy patients, quite often, this coexistence can be overlooked [1,2]. Studies in this field have demonstrated that depression, anxiety disorders and schizophrenia are the most common psychiatric disorders comorbid with epilepsy [3].

Psychogenic non-epileptic seizures (PNES) are seizures that look like epileptic seizures but are not caused by sudden abnormal electrical discharges in the brain. The nature of the symptoms associated with PNES (seemingly neurological yet in fact psychogenic) requires the engagement of a multidisciplinary health team in order to achieve the proper diagnosis and treatment of the patient. Early correct diagnosis is often elusive taking an average of 7.2 years to be reached [1]. Iatrogenic complications may occur when the condition ...

Psychogenic non-epileptic seizures (PNES) are seizures that look like epileptic seizures but are not caused by sudden abnormal electrical discharges in the brain. The nature of the symptoms associated with PNES (seemingly neurological yet in fact psychogenic) requires the engagement of a multidisciplinary health team in order to achieve the proper diagnosis and treatment of the patient. Early correct diagnosis is often elusive taking an average of 7.2 years to be reached [1]. Iatrogenic complications may occur when the condition ...

The relationship between epilepsy and psychosis has been recognised since the mid-nineteenth century. For pragmatic reasons, psychotic symptoms are always grouped according to their temporal relationship to seizures: ictal, peri/para-ictal and interictal psychoses (IIP). Psychoses without a clear relationship to seizures are usually defined IIP and they usually account for 10–30% of all psychoses of epilepsy in unselected case series with a combined prevalence rate of 5.6% in unselected samples, up to 7.0% when considering only temporal lobe epilepsy.

The relationship between epilepsy and psychosis has been recognised since the mid-nineteenth century. For pragmatic reasons, psychotic symptoms are always grouped according to their temporal relationship to seizures: ictal, peri/para-ictal and interictal psychoses (IIP). Psychoses without a clear relationship to seizures are usually defined IIP and they usually account for 10–30% of all psychoses of epilepsy in unselected case series with a combined prevalence rate of 5.6% in unselected samples, up to 7.0% when considering only temporal lobe epilepsy.

Sleep problems are one of the most common comorbidities in epilepsy [1]. The available research indicates that children with epilepsy have a higher frequency of sleep problems than both their healthy siblings and healthy control subjects [2,3]. Multiple types of sleep problems, mainly based on parent-rated tools, have been reported including difficulty on initiating and maintaining sleep, sleep-disordered breathing, parasomnias and excessive daytime sleepiness [4].

Sleep problems are one of the most common comorbidities in epilepsy [1]. The available research indicates that children with epilepsy have a higher frequency of sleep problems than both their healthy siblings and healthy control subjects [2,3]. Multiple types of sleep problems, mainly based on parent-rated tools, have been reported including difficulty on initiating and maintaining sleep, sleep-disordered breathing, parasomnias and excessive daytime sleepiness [4].

The average delay from first seizure to diagnosis of psychogenic non-epileptic seizures (PNES) is over 7 years. The reason for this delay is not well understood. We hypothesized that a perceived decrease in seizure frequency after starting an anti-seizure medication (ASM) may contribute to longer delays, but the frequency of such a response has not been well established.

Revealing the etiology of transient impairments of consciousness is an interdisciplinary task, which often remains unsuccessful despite a wide range of available diagnostic tests. From a neurological perspective it is important to discriminate epileptic and non-epileptic events. Syncopes and psychogenic non-epileptic seizures in particular can be difficult to distinguish from epileptic seizures.

Brain tumor related epilepsy is an important aspect of the burden of disease for patients with glioma and often pose a therapeutic challenge. The risk of epileptic seizures is 70-90% for patients with low grade glioma (LGG) and 30-60% for patients with high grade glioma (HGG) [1–5]. In this study, we explored status epilepticus (SE) in a prospective patient database with glioma and epilepsy. SE is a life-threatening medical emergency in which seizure activity continues for a prolonged period of ...