Response to “Response to Zhang et al: Levetiracetam vs. brivaracetam for adults with refractory focal seizures: A meta-analysis and indirect comparison”

We read with the interest the letter to the editor submitted by Simon Borghs and his colleagues about their methodological concerns about our work and their disagreement with our conclusions [1]. We always welcome different points of view. However, we would like to stress two points. Firstly, as stated in our paper, our work was conducted in strict accordance with Cochrane Review Methods ( and the PRISMA statement (preferred reporting items for systematic reviews and meta-analyses) [1,2].