Stopping epilepsy treatment in seizure remission: good or bad or both?

The ideal objective of treating a person with epilepsy is of course to induce remission by usage of antiepileptic drugs (AEDs) and ultimately stop the antiepileptic drugs AEDs without causing seizure recurrence [1]. Nearly 70% of patients with new-onset epilepsy eventually enter prolonged terminal seizure remission during treatment with AEDs [2,3]. The continued use of AEDs in children and adults may be associated with adverse effects in a substantial fraction of the exposed population, including behavioural and cognitive and other chronic side effects [1].

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