Stereo-EEG, radiofrequency thermocoagulation and neuropathological correlations in a patient with MRI-negative type IIb focal cortical dysplasia

Epilepsy surgery is particularly effective in patients with type II focal cortical dysplasia (FCD), with a seizure freedom rate of up to 85% [1] that is probably due to an overlap between the anatomical lesion and the Epileptogenic Zone (EZ). In some cases, when the EZ is not properly identified, an invasive stereo-electro-encephalography (SEEG) may be required. During SEEG recordings, radiofrequency thermocoagulation (RF-THC) can be performed since there is increasing evidence that it can be beneficial to treat focal epilepsy particularly in patients with epileptogenic nodular heterotopy [2].

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