Simple partial seizures aggravated or induced by benzodiazepine injection

Seizure aggravation by antiepileptic drugs (AEDs) is increasingly recognized as a common problem, particularly in idiopathic generalized epilepsy (IGE). Benzodiazepines (BZDs) are one type of the main AEDs, especially in the treatment of status epilepticus. Paradoxical worsening of seizures associated with BZD is uncommon and most reports are among pediatric patients [1–3]. We report the case of an adult epilepsy patient with simple partial seizures that were aggravated or induced by BZDs.

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