Evaluation of Autonomic tone and cerebral hemodynamics in children with Dravet syndrome

Dravet syndrome (DS) is a developmental and epileptic encephalopathy, with significant risk of mortality due to sudden unexpected death in epilepsy patients (SUDEP) or status epilepticus [1]. Our previous work demonstrated 58% genetic yield of underlying variant in the alpha 1 subunit of the sodium channel encoded by the SCN1A gene in North Indian cohort [2]. Other important reported causative genetic variants in DS are SCN2A, SCN1B, PCDH19 [3].

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