Electroencephalogram Microstate Analysis in Temporal Lobe Epilepsy: A Comparative Study with and without Anxiety

Epilepsy is a chronic neurological disease that affects more than 70 million people worldwide1, 2. Temporal lobe epilepsy (TLE) is a common seizure type of epilepsy, and a number of studies have reported that TLE is related to mood disorders3. Anxiety is one of the most common comorbidities of epilepsy, and the prevalence of anxiety in adult patients with epilepsy is about 11.0%–39.4%4. A survey found that the suicide rate of patients with epilepsy and anxiety was 11.4 times that of the control population without mental disorders and epilepsy5.

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