Drug-resistant epilepsy (DRE), which accounts for about 30% of children with epilepsy, is defined as the failure to obtain persistent seizure independence with two well-tolerated, carefully selected, and used antiepileptic medications [1,2] DRE poses a significant burden. Uncontrolled seizures may cause disruptions in daily activities, impairment in cognitive functions, and increased risk of injury. DRE has also been linked to an increased risk of developmental delays, cognitive disabilities, and psychosocial issues including anxiety and depression.
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