Epilepsies are diverse brain disorders characterized by unprovoked recurrent seizures [1]. Epilepsies contribute significantly to the global disease burden, affecting over 60 million people worldwide of all ages [2]. The underlying pathogenesis remains poorly understood and many patients continue to suffer from uncontrolled seizures [3,4]. Epilepsies are divided by seizure onset into two broad groups; focal epilepsies and generalized epilepsies, the latter being predominantly composed of genetic generalized epilepsies (GGE).
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