Evaluation of burden of SCN1A pathogenicity in North Indian children with Dravet syndrome

Dravet syndrome is an important cause of infantile-onset developmental and epileptic encephalopathy. It is characterized by initial normal development, seizure onset in infancy often triggered by vaccination or febrile illness, frequent and prolonged febrile seizures, afebrile seizures, and developmental stagnation evident by the second year [1]. It is a devastating disorder that causes significant morbidity and has an economic impact on caregivers and hospitals.

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