Seizure Outcome in Drug-Resistant Epilepsy in the Setting of Polymicrogyria

Polymicrogyria (PMG) is a malformation of cortical development (MCD), and is categorized under MCD secondary to abnormal postmigrational neuronal development [1–4]. In addition to a spectrum of neurological diseases, 65-87% of patients with PMG develop epilepsy, and the majority encounter seizure activity within the first five years of life[1]. Approximately 65% of patients with PMG-related epilepsy exhibit drug-resistant epilepsy (DRE). Epilepsy surgery should be explored in these patients with PMG-related DRE [1,5,6].

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