Magnetic Resonance-Guided Laser Interstitial Thermal Therapy Versus Open Surgical Corpus Callosotomy for Pediatric Refractory Epilepsy: A Systematic Review and Meta-Analysis

Medically refractory epilepsy (RE) is a debilitating condition that can significantly impact pediatric patients and surgery is a valuable treatment option for this population. Corpus callosotomy (CC) is an effective surgical procedure that involves interrupting the interhemispheric commissural white matter fibers to prevent the spread of secondary generalized epileptic seizures from one hemisphere to the other[1-4]. This procedure was initially reserved for palliative purposes in patients with severe neurologic impairment or injuries caused by epilepsy.

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