Epilepsy is chronic diseases of central nervous system (CNS) caused by abnormal discharge of brain neurons and is usually accompanied by mental disorders and cognitive dysfunction. There are approximately 70 million epilepsy patients worldwide [1,2]. Although epileptic symptoms are controllable in the majority of patients, approximately 1/3 of epilepsy patients still cannot be effectively controlled by anti-seizure medication(ASM) [2]. Neuroinflammation plays an important role in the seizure process, seizures lead to neuronal and glial cell damage and inflammatory response.
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