Epidemiology and outcome of infantile spasms in Denmark in 1996-2019

The rare seizure type infantile spasms is frequently part of the infantile epileptic spasm syndrome (IESS, previously named ‘West syndrome’), which is an epileptic encephalopathy with a high risk of drug-resistant epilepsy [1]. Seizure onset occurs at age 3-12(24) months and the majority of children develop a severe neurodevelopmental outcome [1]. IESS can be associated with multiple aetiologies, including structural brain abnormalities, hypoxic-ischemic encephalopathy, neurogenetic and neurometabolic diseases [2].

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