Late-onset epilepsy clinic: From clinical diagnostics to biomarkers

Shakespearean sentiments notwithstanding, there is a lot in a name, especially in medicine! A prime example is “late-onset epilepsy”, where the compound words instantaneously suggest that there is something special and unique about this epilepsy that justifies a distinct nomenclature. However, there is no universally accepted definition for late-onset epilepsy (LOE). So far, we have taken a reductionist approach in defining LOE as seizure onset beyond a sharp age cut-off, which in the literature ranges from 50 to 70 years, with 60 or 65 years as the most used demarcation.

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