According to the International League Against Epilepsy (ILAE), drug-resistant epilepsies (DRE) are defined as epilepsies resistant to two or more antiseizure medicines (ASM), appropriately chosen and used whether as monotherapies or in combination [1]. DRE is a challenging condition that affects approximately 10-20% of all children with epilepsy [2-6.]. According to other studies this percentage even rises to 30-40% [7–10].
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