A case-control evaluation of Spasm control and Tolerability of the Modified Atkins diet versus classic ketogenic diet in Chinese Children with infantile epileptic spasms syndrome

Infantile epileptic spasms syndrome, as an age- specific epileptic encephalopathy, is characterized by clustering spasms, electrographic hypsarrhythmia, and frequent developmental regression [1]. However, there are limited available therapies that have proven to be beneficial for this medical condition. The proposed first-line treatment options are adrenocorticotropic hormone (ACTH), oral corticosteroids, or vigabatrin, while any other treatments are less effective or lack proper evidence for their use [1–3].

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