Vitamin B12 is one of the essential water-soluble vitamins which can produce clinical symptoms affecting various major organ systems [1]. Hematological and neurological manifestations are more common in patients with vitamin B12 deficiency [2]. While in adults and adolescents, vitamin B12 has been known to cause peripheral neuropathy, sub-acute combined degeneration of the cord and neuropsychiatric features as predominant neurological manifestations, in infants, especially in Indian subcontinent, infantile tremor syndrome (ITS) has also been etiologically linked to nutritional vitamin B12 deficiency (NVBD) [3,4].
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