Anti-seizure medications (ASMs) are commonly prescribed in older adults as the risk of recurrent unprovoked seizures (epilepsy incidence) in the adult population increases exponentially in older age.[1,2] Resultantly, seizure prevalence approximately doubles between age 50 and 80 and commonly co-occurs with other comorbidities such as cerebrovascular or neurodegenerative disease.[3] Older adults may be particularly vulnerable to the side effects of ASMs because of aging-associated metabolic changes.
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