Poo Matters! A scoping review of impact of constipation on epilepsy

Epilepsy is a chronic neurological disorder, caused by excessive or abnormal neuronal discharges in the brain [1] that predisposes to recurrent seizures [2]. It is a common neurological condition, affecting approximately 600,000 people in the United Kingdom (UK) [3]. Epilepsy has a multifactorial aetiology, ranging from single gene mutations to a complex interplay between genetic and environmental factors [4], and overall heritability estimates of 32% have been reported in the literature [5]. The consequences of an epilepsy diagnosis reach far beyond physical health implications alone, and can result in loss of education, employment, and independence [6], thus contributing to poorer socioeconomic outcomes [7].

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