Clinical factors predictive of new-onset seizure in patients with AIDS-related brain parenchymal lesion

Symptomatic neurological diseases occur in about 40–70% of HIV/AIDS patients during the course of their illness [1–3], even in the era of combined anti-retroviral treatment (cART). Seizure is a common manifestation and plays an important role in the clinical presentation and quality of life of the HIV-infected patients [2,4]; therefore, it is of key concern owing to its lifelong impact and potential for causing brain damage [5]. Approximately 6.2–11% of HIV-infected patients had new-onset seizures [6–8].

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