Epilepsy of infancy with migrating focal seizures (EIMFS) is an early infantile epileptic encephalopathy characterized by resistant focal seizures which migrate from one hemisphere to the other, developmental delay and acquired microcephaly. The signature electroencephalogram (EEG) shows multifocal epileptiform discharges with electrographic seizures restricted to a hemisphere that switches to the opposite side. EIMFS is a genetic disease and most cases are due to de novo mutation in the voltage-gated potassium channel subunit gene KCNT1 [1].
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