The net impact of clinical seizures on outcome characteristics in infants with neonatal encephalopathies at 12 months of age

Neonatal encephalopathy (NE) is one of the most common neurological disorders in the neonatal intensive care unit (NICU). Recent diagnostic advances have changed the etiologic distribution of NE in preterm and term newborns in the last decade [1–6]. Neuroimaging studies using magnetic resonance imaging modalities, such as conventional, diffusion, and spectroscopy, provide a helpful guide regarding the etiologic definition and the pattern of brain injury [7]. Detecting the exact etiology of NE in each newborn has implications for optimal treatment, management, and outcome.

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