Approximately 1 in 26 people will develop epilepsy in their lifetime [1] and approximately 1 in 3 persons with epilepsy will be refractory to antiseizure medications (ASMs) [2]. In the United States of America (USA), with an estimated three million adults and half a million children with epilepsy [3], that translates into approximately one million people with refractory epilepsy [4, 5].
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