Characteristics associated with drug resistant epilepsy in children up to 36 months old with Congenital Zika Syndrome

In November 2015, the Brazilian Ministry of Health declared the Zika virus (ZIKV) outbreak a public health emergency following an increase in microcephaly cases, especially in northeastern Brazil. [1] Since the beginning of reports of children with Congenital Zika Syndrome (CZS), epileptic seizures are the main clinical complication in the first 4 months of life [2]; they tend to be early [3,4] and refractory. [4]