ROLE OF HUMAN LEUKOCYTE ANTIGEN IN ANTI-EPILEPTIC DRUGS-INDUCED STEVENS-JOHNSON SYNDROME/TOXIC EPIDERMAL NECROLYSIS: A META-ANALYSIS

Antiepileptic drugs (AEDs) are the most important of the treatments available for the management of epilepsy [1]. AEDs are classified into conventional and newer AEDs. Conventional AEDs include carbamazepine (CBZ), clobazam, phenobarbital (PB), phenytoin (PHT), and valproic acid (VPA). Newer AEDs include felbamate, gabapentin (GBP), lamotrigine (LTG), levetiracetam (LVT), oxcarbazepine, tigabine, topiramate, vigabatrin, lacosamide, and zonisamide (ZNS) [1, 2]. Antiepileptic drugs are used for the management of not only epilepsy but also neuropathic pain, bipolar disorders, and other comorbidities associated with seizures [1].

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