A Review On Role Of Metformin As a Potential Drug For Epilepsy Treatment And Modulation Of Epileptogenesis

Epilepsy is a chronic neurological disorder that is personified with a high propensity to develop seizures; and is associated with social, cognitive, and psychological consequences [1]. Epilepsy contributes to a third of the burden of neurological diseases worldwide, affecting about 65 million people [2,3]. Seizures may be a result of almost any neurological insult, including trauma, tumors, infection, autoimmune diseases, genetic mutations, etc. Care for persons with epilepsy currently aims at reducing seizure frequency, minimising adverse effects of anti-seizure medications (ASMs) treatment, improving mental and physical comorbidities, and achieving a good quality of life.

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