Sudden unexpected death in epilepsy (SUDEP) is a leading cause of sudden death in patients with epilepsy, and the incidence of SUDEP ranges from 1.1 to 5.9 per 1000 patient-years in epilepsy clinic populations [1–3]. Presence of generalized convulsive seizure (GCS) and ≥3 GCS per year have been proved to be associated with a higher risk of SUDEP [3–5]. Although the mechanism of SUDEP remains controversial, recent studies have focused on determining pathophysiology and electroclinical risk factors for SUDEP as well as biomarkers of GCS severity.
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