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Epilepsy is a common neurological disease, which affects approximately 3.9–5.1% of children in China [1]. Antiseizure medication (ASM) is effective in most patients; however, some patients develop drug-resistant epilepsy. A meta-analysis evaluated that approximately 15–30% patients with epilepsy would progress to drug-resistant epilepsy [2]. Drug-resistant epilepsy can result in cognitive and behavioural problems, autism, poor quality of life, and an increased risk of death [3]. The ketogenic diet (KD) is a high-fat, low-carbohydrate diet which also provides adequate amounts of protein and other nutrients, and it is effective and safe for children with drug-resistant epilepsy [4, 5].