Blog

Thrombocytopenia, defined as a platelet count <150 .109/L, is associated with an increased bleeding risk. Drug-induced thrombocytopenia (DIT) is an important cause with an estimated incidence of 10 cases per million people/year. Although the incidence is higher in adults, DIT can also be seen in children. [1] The underlying pathogenetic mechanism of DIT can be diverse encompassing either a reduced platelet production or an increased clearance of platelets into the circulation. The latter is most often immune with an antibody mediated destruction of platelets.