Sodium channel blockers are effective for benign infantile epilepsy

Benign infantile epilepsy (BIE) is characterized by onset in infancy (with typical development before onset), no underlying disorders, seizure clusters, short seizure duration, and normal interictal electroencephalogram.[1-3] BIE can be familial [3,4] and proline-rich transmembrane protein 2 (PRRT2) gene is a major causal factor.[4,5] The long-term outcome of BIE is favorable, with seizure cessation before 2 years of age [6] and no cognitive or behavioral problems.[7]

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