Postoperative seizure and developmental outcomes of children with hemimegalencephaly and drug-resistant epilepsy

Hemimegalencephaly (HMEG) belongs to the brain overgrowth spectrum with unilateral megalencephaly involving one or almost one entire brain hemisphere [1]. Developmental delay, contralateral hemiparesis, and drug-resistant epilepsy are common in children with HMEG [2, 3]. Early epileptic seizures usually evolve into epileptic encephalopathies and lead to severe psychomotor retardation without intervention [4].

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