Female Preponderance in Genetic Generalized Epilepsies

Epilepsy is a common neurological disorder affecting 45.9 million individuals worldwide1. Sex is usually not considered a susceptibility factor for epilepsy, but differences in epilepsy incidence and prevalence between men and women have been reported2-6. It is slightly more prevalent in men (329.3 per 100.000 population) than in women (318.9 per 100.00 population)1. Men with epilepsy have higher disability-adjusted life-years rates (201.2 per 100.000 population) and higher mortality rates (2.09 per 100000) than women (163.6 per 100000 population and 1.4 per 100000, respectively)1.

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