Serotonin syndrome (SS) is an iatrogenic drug‑induced clinical syndrome characterized by a combination of altered mental activity, neuromuscular abnormalities, and autonomic disturbances. Serotonin syndrome typically results from the increased intrasynaptic concentration of serotonin or 5-hydroxytryptamine (5-HT). There are seven types of 5-HT receptors (5-HT1 to 5-HT7), each with several subtypes. The 5-HT2A and 5-HT1A are the two main receptors implicated in the pathophysiology of SS [1].
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