Ictal hypoperfusion and iron deposition in symptomatogenic zone of epilepsia partialis continua – a case report

Epilepsia partialis continua (EPC) is a form of focal motor status epilepticus and a common symptom of patients with Rasmussen’s encephalitis. During paroxysmal epileptic seizures, regional cerebral blood flow is known to be increased. [1] Dysfunction of the blood-brain barrier (BBB) has been reported to be temporally and anatomically associated with epileptic seizures. [2] In this single case report, we applied a multimodal neuroimaging protocol including arterial spin labeling (ASL) perfusion imaging and quantitative susceptibility mapping (QSM) to contrast ictal and interictal conditions and to elucidate pathophysiological underpinnings of an epileptic seizure.

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