Anxiety symptoms are the strongest predictor of quality of life in temporal lobe epilepsy

Psychiatric disorders occur more often in persons with epilepsy (PWE) than in the general population and persons with other neurological diseases [1]. The prevalence of depressive disorders ranges from 30% to 50%, and though neglected for a long time, anxiety disorders occur in 25 to 52% [2–5], with prevalence of 19.6% for anxiety disorders in persons with drug-resistance epilepsy [4]. Interictal psychiatric disorders and symptoms increase the burden of living with epilepsy [2], and are associated with adverse outcomes, poor quality of life, increased suicide risk, drug-resistance, and worse surgical outcomes [1,2].

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