Brain functional connectivity patterns in focal cortical dysplasia related epilepsy

Focal cortical dysplasia (FCD), often caused by abnormal neuronal growth, is strongly associated with epilepsy and neurodevelopmental disorders [1,2]. Drug-resistant epilepsy is a common characteristic in FCD [3]. Local lesions have been clearly linked to seizure onset, and anomalies in gray matter structure and interhemispheric connections are often observed beyond the primary lesion [4,5].