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During the pandemic of SARS-CoV-2, which began in December 2019, reported symptoms of; COVID-19 are primarily associated with respiratory or gastrointestinal issues. Studies also show that; a significant proportion of patients develop neurological symptoms; up to 36 %. Several case reports describe new onset seizures in COVID-19, especially in severe forms of the infection (1). However, the majority report brief, self-limiting seizures the impact of which seems to have been limited; in contrast we report the case of a 17-year-old female who sustained significant cortical injury during the course of COVID-19 associated multi-inflammatory syndrome.