Blog

Febrile seizures (FS), the most common seizures observed in pediatric patients, affect 2-5% of children below 5 years of age [1,2]. These are characterized by fever episodes without any history of neurological insults or spontaneous seizures [3]. Many studies on family and twins have demonstrated that genetic factors play an important role in FS [4,5]. Approximately one-third of children with FS show a positive family history [4]. Possible modes of inheritance for genetic predisposition to FS are autosomal dominance with reduced penetrance and polygenic or multifactorial inheritance [6,7].