Therapeutic Effect of Intravenous Levetiracetam in Status Epilepticus:A meta-analysis and systematic review

Status epilepticus (SE) often resulting in serious complications and even death if can’t be controlled in time, and so be considered as the most extreme form of seizure [1]. The abnormality of epileptic inhibition or trigger mechanism makes it difficult to stop [1]. Epidemiological investigations have shown that the incidence rate is 41–61 per 100,000 individuals per year [2]. Due to high fever, circulation failure, aspiration or neuronal toxicity, irreversible brain injury and pulmonary infection often occurred, leading to high mortality and high disability rates [3].

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