Comparison between the Neurological Disorders Depression Inventory for Epilepsy and the Patient Health Questionnaire-9 in patients with epilepsy according to antiepileptic drug load

Depression is common in patients with epilepsy (PWE): the prevalence of depression in PWE is about five times higher than in the general population [1,2]. The pathophysiological and psychosocial features of epilepsy put individuals at greater risk of depression, and conversely, depression has an adverse effect on epilepsy [3]. Depression is significantly associated with drug-resistant epilepsy and poor quality of life [4,5]. Together with depression, suicide is also a serious problem in PWE. The suicide rate in PWE is about three times higher than in the general population, and is higher when accompanied by depression [6].

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