Influence of new versus traditional antiepileptic drugs on course and outcome of status epilepticus

Status epilepticus (SE) is a frequent neurological emergency with an incidence of 16 to 36/100,000 [1,2]. The prognosis of SE is largely determined by unmodifiable patient characteristics like age, a history of previous seizures, the patient’s premorbid functional status, the seizure semiology, EEG patterns, and particularly the etiology underlying the SE [3–8]. However, prolonged SE duration also contributes to poor prognosis, mirrored by mortality rates of 25% in refractory SE as compared to approximately 10% in non-refractory SE [9,10].

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