Optimized SEEG-guided radiofrequency thermocoagulation for mesial temporal lobe epilepsy with hippocampal sclerosis

Mesial temporal lobe epilepsy associated with hippocampal sclerosis (MTLE-HS) remains of special interest due to its high prevalence and frequent drug-resistance [1]. Standard surgical approaches including anterior temporal lobectomy (ATL) or selective amygdalohippocampectomy (SAH) are established effective treatments in medically refractory MTLE-HS patients. Prospective, randomized trials have demonstrated seizure-free rates significantly greater in surgically-treated patients compared to those given best medical therapy [2–4].

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