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Adverse drug reactions (ADRs) are a well-known and often limiting problem in the pharmacological treatment of epilepsies. Cutaneous drug reactions – ranging from mild maculopapular exanthema (MPE) to severe Stevens-Johnson syndrome/ toxic epidermal necrolysis (SJS/TEN) are frequently observed in association with several antiepileptic drugs (AEDs) [1]. DRESS (drug reaction with eosinophilia and systemic symptoms) is a potentially life-threatening subtype that features hypereosinophilia, morbilliform skin eruptions, fever, facial edema, enlarged lymph nodes and other organ involvement and occurs with a latency of 2 to 6 weeks [2].